The effect of carbon dioxide gas on the occurrence of nephropathy

Comparison of carbon dioxide gas and contrast agent on kidney function in patients peripheral vascular disease

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191107045359N1

Enrollment

166

Registered

2019-12-18

Start date

2019-11-22

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral vascular diseases.

Interventions

Intervention 1: Intervention group: Angiography or angioplasty with CO2 gas. Intervention 2: Control group: Angiography or angioplasty with contrast media.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Estimated GFR greater than 30 ml / min /1.73 m2 based on MDRD equation

Exclusion criteria

Exclusion criteria: Contact contrast over the past month Patients with intracardiac shunt History of kidney or heart transplantation More than 15% change in serum creatinine level over the past two days Patients undergo regular hemodialysis Patients with a history of proteinuria Cirrhotic patients

Design outcomes

Primary

Measure	Time frame
Contrast induce acute kidney injury.Nephropathy will be defined based on a 25% or 0.5 mg / dl increase in serum creatinine. Timepoint: Before intervention and 48 hours after intervention. Method of measurement: laboratory kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBatoul Naghavi

Iran University of Medical Sciences

naghavirhc@gmail.com+98 21 2266 3246

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026