Aphthous stomatitis. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: Intervention group: Patients will use 7% of pentoxifylline adhesive mucus gel prepared at Shahid Sadoughi School of Pharmacy in Yazd twice a day at the rate of one drop per lesion. At
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with aphthous stomatitis starting up to two days No pregnancy and lactation Patients between 18_65 years old No history of allergies to aloe vera and thymol
Exclusion criteria
Exclusion criteria: Patients with skin diseases Sensitivity to aloe vera and thyoml or any of components of the product Do not use the drug for two consecutive days Exacerbation of the aphthous stomatitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: At the beginning of treatment and after every 2 to 10 days, the condition of aphthous lesions is evaluated for pain intensity (score 0 to 4). Method of measurement: Scoring pain using a questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Redness and inflammation. Timepoint: At the beginning of treatment and after every 2 to 10 days, the condition of aphthous lesions is evaluated for the severity of redness and inflammation (score 0 to 4). Method of measurement: Scoring severe redness and inflammation using a questionnaire.;Total area of ??aphthous lesions. Timepoint: At the beginning of treatment and after every 2 to 10 days, the condition of the aphthous lesions is evaluated in terms of the total area of ??the aphthous lesions. Method of measurement: Determining the total area of ??aphthous lesions through Fiji software. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohsen Zabihi
Yazd University of Medical Sciences
Outcome results
None listed