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Comparative Efficacy and Safety of Betamethasone Shampoo versus Ketoconazole Shampoo in the treatment of Seborrheic Dermatitis

Comparative Efficacy and Safety of Betamethasone Shampoo versus Ketoconazole Shampoo in the treatment of Seborrheic Dermatitis : A experimental and Randomized controlled clinical Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191106045356N22
Enrollment
60
Registered
2024-12-16
Start date
2024-12-20
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seborrheic Dermatitis.

Interventions

Intervention 1: Intervention group: Participants will use Ketoconazole shampoo (2%) twice weekly for6 weeks. Intervention 2: Intervention group: Participants will use betamethasone shampoo (0.1 %) twi

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Adults aged 18 to 65 years with a diagnosis of seborrheic dermatitis Mild to moderate severity of seborrheic treatment (determined by a standard scoring system).

Exclusion criteria

Exclusion criteria: Severe seborrhoeic dermatitis that requires systemic treatment Using other local or systemic treatments in the last 4 weeks Known hypersensitivity or contraindications to ketoconazole or betamethasone The presence of other skin conditions that may interfere with the evaluation of seborrheic dermatitis. Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
Reducing the severity of seborrheic dermatitis symptoms. Timepoint: At the end of 6th week,the reduction in the severity of symptoms is measured. Method of measurement: Seborrheic Dermatitis Area and Severity Index (SDASI).

Secondary

MeasureTime frame
Relief of patient-reported symptoms including itching, scaling, and redness. Timepoint: The rate of recurrence is measured at weeks 2, 4, and 6. Method of measurement: Visual Analogue Scale and Dermatology Life Quality Index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Zabihi

Yazd University of Medical Sciences

mzabihi100@gmail.com+98 35 3820 3419

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026