The effect of topical piroxicam in the treatment of uremic pruritus

The effect of topical piroxicam in the treatment of uremic pruritus: A randomized double-blinded placebo control clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191106045356N18

Enrollment

Registered

2023-07-25

Start date

2023-03-06

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uremic pruritus. Pruritus

Interventions

Intervention 1: Intervention group: 25 patients with uremic pruritus treated with 0.5% piroxicam gel (manufactured by a domestic pharmaceutical company), topical application, once a day for 14 days. I

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients undergoing hemodialysis more than 3 times a month Insensitivity to piroxicam Patients with chronic uremic pruritus Absence of pregnancy and breastfeeding

Exclusion criteria

Exclusion criteria: Patients with underlying skin disease Allergic to Piroxicam Pregnancy

Design outcomes

Primary

Measure	Time frame
Uremic pruritus. Timepoint: ?Before intervention and 7, 14 days after intervention. Method of measurement: Pruritus questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Zabihi

Yazd University of Medical Sciences

mzabihi100@gmail.com+98 35 3820 3419

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026