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Evaluation of the effect of glycyrrhizin hydrogel on laser burns

Preparation and evaluation of topical glycyrrhizin-menthol-aloe vera gel and assessment its effect on the prevention of laser-induced dermatitis: a randomized controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191106045356N17
Enrollment
60
Registered
2023-07-24
Start date
2023-04-09
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laser induced dermatitis. Other specified disorders of the skin and subcutaneous tissue related to radiation

Interventions

Intervention 1: Intervention group: The recipient of glycyrrhizin-menthol-aloe vera gel will use the prescribed medicine twice a day under the supervision of a doctor. In this study, clients who have

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Clients starting to use laser Clients aged 18 to 55 years No history of licorice allergy Absence of severe systemic disease such as uncontrolled diabetes, epilepsy, immune system deficiency, etc. Willingness to participate in the study and complete the ethical consent form

Exclusion criteria

Exclusion criteria: Clients with skin disease Allergy to glycyrrhizin or any of the compounds used Exacerbation of dermatitis or 2nd degree burns Non-cooperation of the volunteer in using medicine for more than one day

Design outcomes

Primary

MeasureTime frame
Grading the intensity of skin redness. Timepoint: After starting treatment at times 1, 2, 4, 7, 10, 15. Method of measurement: The condition of the laser site in terms of the loss of the epidermis, the intensity of redness, dryness, itching, burning, and pain (based on the visual analog scale), and the patient's satisfaction with the use of the drug, and that the skin of the laser area has undergone second-degree burns. are evaluated or not, as well as the need to use the standard treatment of dermatitis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Dehghani

Yazd University of Medical Sciences

fatemehdehqani978@yahoo.com+98 913 776 2437

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026