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Evaluation of the effects of thymol vaginal cream on bacterial vulvovaginitis

Evaluation of the effectiveness of Thymol vaginal cream on improving symptoms in patients with bacterial vulvovaginitis; A double-blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191106045356N12
Enrollment
60
Registered
2022-08-14
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial vulvovaginitis (Trichomonas vaginalis). Trichomonal vulvovaginitis

Interventions

Intervention 1: Intervention group: patients with bacterial vulvovaginitis treated with topical thymol vaginal cream 5 mg, every night for up to one week. Intervention 2: Control group: Patients with

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Female Married Patients with bacterial vulvovaginitis based on ASMEL criteria Willingness to participate in the study and complete the ethical consent form

Exclusion criteria

Exclusion criteria: Irritation or allergic reaction to the drug Aggravation of symptoms caused by infection Not taking medicine for more than one day Women who are pregnant, breastfeeding, have immune deficiency or malignancy History of mental disorders and psychosis Allergic reactions following consumption of thymol or products containing thymol

Design outcomes

Primary

MeasureTime frame
Complaints and clinical observations. Timepoint: Evaluation of complaints and clinical observations on days 1, 3 and 7 days after starting the use of thymol vaginal cream. Method of measurement: Likert scale.

Secondary

MeasureTime frame
Clinical observations and complaints. Timepoint: At the beginning of the study and after days 1, 3 and 7 days after starting to use the vaginal cream. Method of measurement: Likert scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Zabihi

Yazd University of Medical Sciences

mzabihi100@gmail.com+98 35 3724 1171

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026