oral lichen planus. Lichen planus
Conditions
Interventions
Intervention 1: Intervention group: Includes 25 patients who are diagnosed with oral lichen planus based on the patient's examination by a dentist or biopsy of the tissue of one or more ulcers in the
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Women should not be pregnant or breastfeeding Do not use allopurinol Do not use viral vaccines during treatment Patients do not have a confirmed history of allergic reactions following oral administration of azathioprine The patient does not have a low level of consciousness The patient should not be treated with warfarin The patient does not have an active viral disease
Exclusion criteria
Exclusion criteria: Do not use the drug for two consecutive days Exacerbation of oral lichen planus lesions Allergic reaction to azathioprine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Redness and inflammation. Timepoint: At the beginning of treatment and after every 2 to 10 days, the status of oral lichen planus lesions is evaluated for the severity of redness and inflammation (score 0 to 4). Method of measurement: Scoring severe redness and inflammation using a Reeda questionnaire.;Severe pain and burning. Timepoint: At the beginning of treatment and after every 2 to 10 days, the condition of oral lichen planus lesions is evaluated for the severity of pain and burning (score 0 to 4). Method of measurement: Severe pain and burning using VAS questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohsen Zabihi
Yazd University of Medical Sciences
Outcome results
None listed