Condition 1: Crohn's disease. Condition 2: Ulcerative colitis. Crohn's disease [regional enteritis] Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group: They will receive 2 capsules of 500 (gdu) containing bromelain manufactured by Salamat Parmon Amin company for 8 weeks, 1 hour before or 2 hours after food. Interv
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Diagnosis of inflammatory bowel disease based on the diagnosis of a gastroenterologist Having mild to moderate disease activity in ulcerative colitis and mild to moderate disease activity in Crohn's Minimum age of 18 years and maximum of 70 years People express their satisfaction to participate in the study
Exclusion criteria
Exclusion criteria: Smoking Alcohol consumption in the last 1 month Pregnancy and breastfeeding The consumption of antioxidant supplements such as Vitamin C, Vitamin E, Selenium, Curcumin, Pomegranate Peel, or any other antioxidant supplements in the last 1 month The consumption of anticoagulant drugs The consumption of drugs against tumor necrosis factor alpha The consumption of steroidal and non-steroidal anti-inflammatory agents, antibiotics, fiber, probiotic during the two weeks before the intervention. Patients in the stage of Vitamin D deficiency. Suffering from other chronic inflammatory diseases, mental disorders, or neurological diseases (such as Parkinson's, Alzheimer's, intracranial hemorrhage, head or brain injury), Cushing's syndrome, polycystic ovary syndrome, anemia, hemophilia, leukopenia, thrombocytopenia, asthma, cancer, anorexia nervosa, bulimia nervosa, other autoimmune diseases, and major gastrointestinal surgeries that may affect the condition under study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcerative colitis disease activity questionnaire score. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Ulcerative Colitis disease Activity Evaluation Questionnaire.;Crohn disease activity questionnaire score. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Crohn disease Activity Evaluation Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life questionnaire score in inflammatory bowel disease. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Quality of life assessment questionnaire in inflammatory bowel disease. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Tayebeh Rahideh
Iran University of Medical Sciences
Outcome results
None listed