Preterm Labor and Mizoprostol

Comparison of Oral Misoprostol Tablets and Oxytocin for the Induction of Labor in Preterm Premature Rupture of Membranes

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191104045333N1

Enrollment

Registered

2020-04-19

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Premature Rupture of Membranes.

Interventions

Intervention group: 50 µg oral misoprostol every 4 hours up to a maximum of 6 doses.

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: ? Definite diagnosis of rupture of membrane on examination with speculum or positive frenne test ? Gestational age between 28 and 37 weeks One Pregnancy Cephalic presentation ? Bishop score =5

Exclusion criteria

Exclusion criteria: Fetal Heart Rate disorder Cesarean section history Placenta Previa Active cardiovascular disease, asthma, glaucoma

Design outcomes

Primary

Measure	Time frame
Induction of labor until delivery. Timepoint: From induction to delivery. Method of measurement: Information will be recorded in terms of the time interval between the start of induction and delivery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSpideh Besharati

Shahid Beheshti University of Medical Sciences

sepideh_besharati@sbmu.ac.ir+98 21 2243 9770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026