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The effect of Nivasha nanosilver spray and sildenafil ointment on wound healing in suppurative appendicitis.

Comparison of the effects of Nivasha Nanosilver Spray and Sildenafil Topical Ointment on Wound Healing in Purulent Appendicitis.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N50
Enrollment
150
Registered
2025-12-31
Start date
2026-01-15
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound infection following suppurative appendicitis. Infection following a procedure

Interventions

Intervention 1: Nanosilver spray group: In this group, Nivasha nanosilver spray is applied to the wound every 8 hours prior to dressing, followed by wound dressing. This treatment is continued until c

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with surgical wounds following suppurative appendicitis. Having informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Presence of kidney disease, liver disease, cardiovascular disease, or malignancy History of narcotic (illicit drug) use and chronic use of analgesics History of hypertension, diabetes, and hematologic and vascular diseases Presence of known hypersensitivity to the study drugs and absence of seasonal allergies

Design outcomes

Primary

MeasureTime frame
Incidence of wound infection. Timepoint: After surgery. Method of measurement: Physical examination.;Pain score. Timepoint: Before intervention, third day, seventh day, and 14th day of treatment. Method of measurement: Visual analog scale.;Wound size. Timepoint: First intervention and after the end of the intervention. Method of measurement: Caliper.;Duration of treatment. Timepoint: After the intervention. Method of measurement: Patient file.;Wound score. Timepoint: Before the intervention and in the first and second weeks after the intervention. Method of measurement: Bates-Jensen Wound Assessment Tool.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Shojaei

Arak University of Medical Sciences

R.shojaei@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026