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The effect of oral zinc on mortality in patients with non-traumatic subarachnoid hemorrhage.

Studying the effect of oral zinc on mortality in patients with non-traumatic subarachnoid hemorrhage

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N47
Enrollment
108
Registered
2025-11-11
Start date
2025-11-11
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nontraumatic subarachnoid hemorrhage. Nontraumatic subarachnoid hemorrhage

Interventions

Intervention 1: Intervention group: Patients in this group will receive an oral capsule of zinc sulfate containing 50 mg of elemental zinc (Alhavi Pharmaceutical Co., Tehran, Iran) either via gavage o

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with non-traumatic subarachnoid hemorrhage Consent to participate in the study

Exclusion criteria

Exclusion criteria: Contraindications to zinc use, including allergy, pregnancy or lactation, malignancy, or neurodegenerative diseases. Medical conditions affecting drug metabolism, such as hepatic or renal disorders, or history of craniotomy. Short hospitalization duration in the treatment center (less than 10 days).

Design outcomes

Primary

MeasureTime frame
Sequential Organ Failure Assessment score. Timepoint: v. Method of measurement: Sequential Organ Failure Assessment scale.;Glasgow Coma Scale score. Timepoint: First, third, seventh, and tenth days after the intervention. Method of measurement: Glasgow Coma Scale.;APACHE II score. Timepoint: First day of intervention. Method of measurement: APACHE II scale.

Secondary

MeasureTime frame
Death. Timepoint: After the intervention. Method of measurement: Patient file.;Occurrence of complications. Timepoint: Beginning of intervention until the tenth day after intervention. Method of measurement: History and physical examination.;Length of hospital stay. Timepoint: After the intervention. Method of measurement: Patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Behnam Arabzadeh

Arak University of Medical Sciences

Behnamarabzade2000@gmail.com+98 38 1495 7558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026