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The effect of sildenafil in improving ovarian torsion

Investigating the effect of sildenafil on vascular reperfusion after ovarian torsion in women with ovarian torsion

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N36
Enrollment
22
Registered
2025-05-06
Start date
2025-05-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian torsion. Torsion of ovary, ovarian pedicle and fallopian tube

Interventions

Intervention 1: Intervention group: After surgery, sildenafil is given to the patient vaginally at a dose of 25 mg every 8 hours for three days. Intervention 2: Control group: After surgery, the patie

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: All patients with ovarian torsion who have been referred to Engineer Sina Rezaei Ashtiani Hospital in Arak. Ovarian detorsion surgery performed by a gynecologist Consent to participate in the study

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding History of allergy to sildenafil

Design outcomes

Primary

MeasureTime frame
PI ovarian artery. Timepoint: Before the intervention, 24 hours and 3 days after the intervention. Method of measurement: Vaginal Doppler Ultrasound.;RI ovarian artery. Timepoint: Before the intervention, 24 hours and 3 days after the intervention. Method of measurement: Vaginal Doppler Ultrasound.;S/D ovarian artery. Timepoint: Before the intervention, 24 hours and 3 days after the intervention. Method of measurement: Vaginal Doppler Ultrasound.;Ovarian volume. Timepoint: Before the intervention, 24 hours and 3 days after the intervention. Method of measurement: Ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Azam Muslimi

Arak University of Medical Sciences

azammoslemi@arakmu.ac.ir+98 86 3383 8319

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026