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Sedation and analgesia of dexmedetomidine, fentanyl, and intrathecal neostigmine in femoral surgery

Comparison of the sedation and analgesia effect of intrathecal dexmedetomidine, fentanyl and neostigmine in femur fracture repair surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N33
Enrollment
135
Registered
2025-04-04
Start date
2025-04-09
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femur fracture repair surgery. Age-related osteoporosis with current pathological fracture, femur

Interventions

Intervention 1: Dexmedetomidine group: Patients receive 5 micrograms of dexmedetomidine (in a volume of 1 ml) manufactured by Exir Company of Iran along with 15 mg of ropivacaine (3 ml of ropivacaine

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for femur fracture repair surgery and refer to Vali Asr Hospital in Arak Consent to participate in the study BMI less than 30 ASA Class One and Two

Exclusion criteria

Exclusion criteria: Presence of kidney, liver, heart disease, and cardiac arrhythmias Allergy to the medications used Psychological problems and absence of peripheral and central neuropathy Local infection in the spinal area

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: Postoperatively, during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: visual analog scale.;Onset of sensory and motor block. Timepoint: After spinal anesthesia. Method of measurement: Minute.;Duration of sensory and motor block. Timepoint: It is measured from the start of spinal anesthesia to its end. Method of measurement: Minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hesamuddin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026