Investigating two medicinal combinations of Ropivacaine-Dexmedetomidine and Ropivacaine-Ketamine by subcutaneous method in postoperative pain control in Inguinal hernia candidate patients

Comparison of the effect of two medicinal combinations Ropivacaine-Dexmedetomidine and Ropivacaine-Ketamine by subcutaneous method in controlling postoperative pain in patients with Inguinal hernia candidates

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191104045328N23

Enrollment

140

Registered

2024-08-17

Start date

2024-06-18

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal hernia. Inguinal hernia

Interventions

Intervention 1: Intervention group: Dexmedetomidine 1 microgram/kg (Exir Pharmaceuticals-Iran) along with ropivacaine 0.75% (3 mg/kg) (Molteni pharmaceutical company, Italy) diluted to reach the final

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidates for inguinal hernia surgery between the ages of 18 and 65 Body mass index below 30 Consent to participate in the study

Exclusion criteria

Exclusion criteria: History of allergy to studied drugs Smoking Underlying disease

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Every 5 minutes. Method of measurement: Pressure gauge device.;Heart rate. Timepoint: Every5 minutes. Method of measurement: Cardiac monitoring.;Complications of dizziness and headache. Timepoint: The end of the intervention. Method of measurement: Ask the patient.;Pain score. Timepoint: The amount of pain during recovery at 2, 4, 6, 12, and 24 hours after the operation. Method of measurement: Visual Analogue Scale Ruler.;Amount of narcotic drug used. Timepoint: 24 hours after surgery. Method of measurement: Patient file.;Duration of pain relief. Timepoint: After surgery. Method of measurement: Watch.	—

Measure

Time frame

Blood pressure. Timepoint: Every 5 minutes. Method of measurement: Pressure gauge device.;Heart rate. Timepoint: Every5 minutes. Method of measurement: Cardiac monitoring.;Complications of dizziness and headache. Timepoint: The end of the intervention. Method of measurement: Ask the patient.;Pain score. Timepoint: The amount of pain during recovery at 2, 4, 6, 12, and 24 hours after the operation. Method of measurement: Visual Analogue Scale Ruler.;Amount of narcotic drug used. Timepoint: 24 hours after surgery. Method of measurement: Patient file.;Duration of pain relief. Timepoint: After surgery. Method of measurement: Watch.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Shojaei

Arak University of Medical Sciences

R.shojaei@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026