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Investigating the effect of atorvastatin and aspirin on the durability and function of the central venous catheter for dialysis

Comparison of the effect of atorvastatin and aspirin on the durability and performance of tunneled catheters in patients who are candidates for central venous catheter insertion for dialysis.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N20
Enrollment
162
Registered
2024-03-28
Start date
2024-03-12
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dialysis. Infection due to central venous catheter

Interventions

Intervention 1: Intervention group: Daily consumption of a 40 mg Atorvastatin tablet of Soban Daru company, along with a placebo aspirin tablet, from the day of catheter placement until 6 months or ca

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patients for central venous catheterization, for whom a tunneled catheter will be implanted. Surgery performed by a surgeon and resident Consent to participate in the study

Exclusion criteria

Exclusion criteria: History of coagulopathy Existence of high blood pressure at the same time as diabetes Presence of fatty liver and liver disease based on confirmation by liver enzyme test The presence of a disease that has contraindications for taking aspirin (such as nasal polyp disease, asthma, allergy to aspirin)

Design outcomes

Primary

MeasureTime frame
Duration of catheter operation. Timepoint: The beginning of the intervention until 180 days later. Method of measurement: checklist.;Incidence of catheter infection. Timepoint: After the intervention. Method of measurement: checklist.;Occurrence of thrombosis. Timepoint: After the intervention. Method of measurement: Clinical examination and ultrasound.

Secondary

MeasureTime frame
180 days operation. Timepoint: After the intervention. Method of measurement: Checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Shojaei

Arak University of Medical Sciences

R.shojaei@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026