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Comparison of the effect of two drugs, azithromycin and doxycycline, on infection after hysterosalpingography

The prophylactic effect of azithromycin and doxycycline in infection caused by hysterosalpingography

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191104045328N15
Enrollment
110
Registered
2023-06-20
Start date
2023-06-22
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection after hysterosalpingography. Acute inflammatory disease of uterus

Interventions

Intervention 1: Intervention group: Before hysterosalpingography, patients in the azithromycin group receive a single dose of 1 gram of azithromycin. Intervention 2: Intervention group: Before hystero

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 18-55-year-old women who are candidates for hysterosalpingography, referring to the obstetrics and gynecology clinic, infertility clinic, Amir-al Mominin Hospital, Arak Consent to participate in the study

Exclusion criteria

Exclusion criteria: History of acute Pelvic inflammatory disease within two months prior to Hysterosalpingography, to prevent incompletely treated or residual active Pelvic inflammatory disease. history of gynecological surgery and other transcervical procedures within two months prior to Hysterosalpingography, to avoid confounding by other gynecological procedures. The use of multiple antibiotics within two months before hysterosalpingography, to identify the exact effect of each of the studied antibiotics without disturbing the interaction of multiple antibiotics.

Design outcomes

Primary

MeasureTime frame
Chlamydial infection. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: Perform PCR.;The need to treat pelvic inflammatory disease. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: History and physical examination.;Satisfaction with prophylaxis. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: A questionnaire made by the researcher.;Fever. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: Thermometer.;Side effects. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: Physical history.;Uterine and cervical infection. Timepoint: 2 weeks after hysterosalpingography. Method of measurement: Physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nazila Najdi

Arak University of Medical Sciences

najdinazila@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026