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Comparison effect of Dexmedetomidine and Granisetron and ketamine to preventing post-operative complications

Comparison of the effect of Dexmedetomidine, Granisetron and Ketamine on preventing post operative shivering after general anesthesia

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191101045300N1
Enrollment
148
Registered
2019-12-28
Start date
2019-08-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal involuntary movements. Hypothermia following anesthesia

Interventions

Intervention 1: Intervention group 1: 0.5 mcg/kg of Dexmedetomidine will be injected intravenously 30 minutes before the end of the surgery. Intervention 2: Intervention group 2: 0.5 mg/kg of Ketamin

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Being at the age of 18 to 65 years old ASA class 1 or 2 Patients candidate for abdominal laparoscopic surgery Satisfaction with study participation BMI<35

Exclusion criteria

Exclusion criteria: Being allergic to the prescribed medicines cardiovascular disease, kidney or endocrine disease smoking and addiction chronic Pulmonary Diseases (Asthma and COPD) pregnancy history of previous laparoscopy or previous laparotomy

Design outcomes

Primary

MeasureTime frame
Post Anesthetic shivering. Timepoint: 0, 10, 20, 30, 40 and 50 minutes after entering to recovery room. 1, 2, 4 and 6 hours after entering to recovery room. Method of measurement: Quality Grading.;Body temperature. Timepoint: 0, 10, 20, 30, 40 and 50 minutes after entering to recovery room. 1, 2, 4 and 6 hours after entering to recovery room. Method of measurement: Digital Termometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamodin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026