Investigation of effects of tissue adhesive on Impacted Third Molar Teeth surgery

Comparison of Silk Sutures and Tissue Adhesives for wound closure of Impacted Third Molar Teeth surgery: Clinical and Histological Evaluation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191030045286N1

Enrollment

Registered

2020-05-12

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impactd teeth. Impacted teeth

Interventions

Intervention 1: Intervention group: 2-ethyl-cyanoacrylate tissue adhesive(EPIGLU,Meyer-Haake Co.Germany) will be used in intervention group for surgery wound closure.Tissue adhesive will be used based

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All subjects of 18 years and above with mesio-angularly impacted mandibular third molar Subjects whitout known systemic disease such as bleeding dyscrasia and immunosuppression Subjects not allergic to the drugs or anaesthetic agents in the surgical protocol Subjects with good oral hygiene Subjects who are non-smokers

Exclusion criteria

Exclusion criteria: Subject with severe caries of the second molar teeth Subject between the age of 18 & 25 who have vertical class 1 and level A pell & gregory classification impaction in third molar teeth

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1,3,7 days after surgery. Method of measurement: by pain Visual Analogue Scale.;Wound dehiscence. Timepoint: 1,3,7 days after surgery. Method of measurement: by visual inspection and by gentle probing with a williams probe.;Vascularity. Timepoint: 7days after surgery. Method of measurement: By microscope.	—

Secondary

Measure	Time frame
Swelling. Timepoint: Befor surgery and 1,3,7 days after surgery. Method of measurement: Average of tragus to pogonion,tragus to commissure and external canthus to gonion.;Trismus. Timepoint: Before surgery and 1,3,7 days after surgery. Method of measurement: Maximum space between mesial and incisal edge of central teeth of maxilla and mandible.;Bleeding. Timepoint: 1,3,7days after surgery. Method of measurement: Visual Analogue Scale.;Wound infection. Timepoint: 1,3,7 days after surgery. Method of measurement: Based on purulent discharge from the surgical site.;Wound closure time. Timepoint: during surgery. Method of measurement: Recording by using a calibrated stop watch.;Inflammatory cell infiltration. Timepoint: 7days after surgery. Method of measurement: By microscope.;Fibroblastic activity. Timepoint: 7days after surgery. Method of measurement: By microscope.	—

Measure

Time frame

Swelling. Timepoint: Befor surgery and 1,3,7 days after surgery. Method of measurement: Average of tragus to pogonion,tragus to commissure and external canthus to gonion.;Trismus. Timepoint: Before surgery and 1,3,7 days after surgery. Method of measurement: Maximum space between mesial and incisal edge of central teeth of maxilla and mandible.;Bleeding. Timepoint: 1,3,7days after surgery. Method of measurement: Visual Analogue Scale.;Wound infection. Timepoint: 1,3,7 days after surgery. Method of measurement: Based on purulent discharge from the surgical site.;Wound closure time. Timepoint: during surgery. Method of measurement: Recording by using a calibrated stop watch.;Inflammatory cell infiltration. Timepoint: 7days after surgery. Method of measurement: By microscope.;Fibroblastic activity. Timepoint: 7days after surgery. Method of measurement: By microscope.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Farokhnia

Ahvaz University of Medical Sciences

farokhnia.ma@ajums.ac.ir+98 990 191 8808

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026