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Effect of moxidectin in treatment of scabies

Efficacy and Safety of moxidectin versus ivermectin for treatment of human scabies: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191030045275N1
Enrollment
100
Registered
2020-02-20
Start date
2641-08-23
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients diagnosed of having scabies. Scabies

Interventions

Intervention 1: Group A (50 patients): Treated by application of topical formulation of moxidectin (Cydectin®) once. Intervention 2: Control group: Group B (50 patients): Treated by application of top

Sponsors

Faculty of Medicine, Tanta University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 60 Years

Inclusion criteria

Inclusion criteria: (A) Clinical: 1. Intense pruritus especially at night. 2. Typical distribution of the excoriated papulovesicular lesions; around umbilicus, flexures, genitalia, interdigital spaces. 3. Affection of other family members. (B) Parasitological: By detection of Sarcoptes Scabeii mites (adult, larvae and eggs) in cutaneous scrapings.

Exclusion criteria

Exclusion criteria: Patients with recent topical or systemic treatments of scabies. Patients with clinical bacterial infection or any other associated skin disease. Patients with any evident systemic diseases causing pruritus. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Clinical lesions and degree of pruritus. Timepoint: 1 week after intervention. Method of measurement: Clinical evaluation.;Mites count. Timepoint: 1 week after intervention. Method of measurement: Microscopic examination of mites.

Countries

Egypt

Contacts

Public ContactDr. Mohamed Fawzy

Tanta University

fawzy208222@yahoo.com+20 122 577 5148

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026