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The effect of intravenous pump dexmedetomidine with paracetamol and ketorolac with paracetamol on pain after cesarean section

The comparison of analgesic effect of intravenous pump dexmedetomidine with paracetamol and ketorolac with paracetamol on postoperative pain after cesarean section

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191025045237N1
Enrollment
60
Registered
2020-12-19
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after cesarean section. Acute pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: Paracetamol 1 g (Exir CO., Iran) and Dexmedetomidine 0.2 µg/kg (Abureihan CO., Iran) soluted in 100 cc normal saline will be injected via analgesic pump (Kanak Tech

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age between 18 to 40 years ASA Class I and II Candidate for elective cesarean section No drug allergies to dexmedetomidine, ketorolac and paracetamol Stable hemodynamics Consent to participate in the study

Exclusion criteria

Exclusion criteria: history of asthma history of bleeding or gastrointestinal ulcer severe liver disease

Design outcomes

Primary

MeasureTime frame
Severity of Pain. Timepoint: The time of 2, 4, 8, 12 and 24 hours after the surgery. Method of measurement: Visual analog scale (VAS).;Hemodynamics changes (Systolic and diastolic blood pressure, heart rate). Timepoint: The time of 2, 4, 8, 12 and 24 hours after the surgery. Method of measurement: Mercury barometer.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: The time of 2, 4, 8, 12 and 24 hours after the surgery. Method of measurement: presence of nausea and vomiting based on direct observation and patients report.;Intensity of patients' anxiety. Timepoint: The time of 2, 4, 8, 12 and 24 hours after the surgery. Method of measurement: Ramsey sedate score (1-6).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Hajilari

Ahvaz University of Medical Sciences

drhh1353@gmail.com+98 61 3222 0168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026