Comparing the effect of dexmedetomidine and sufentanil in reducing forearm fracture pain

Comparing the effect of dexmedetomidine and sufentanil on the quality of forearm fracture undersupraclavicular nerve block

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191025045235N3

Enrollment

118

Registered

2024-11-17

Start date

2025-04-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operation pain. Acute pain due to trauma

Interventions

Intervention group: Patients are divided into two groups. In the dexmedetomidine group, 4mg/kg of lidocaine and 1 micro/kg of dexmedetomidine will be used in the epinephrine syringe using distilled wa

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients between 20 and 60 years, ASA class 1,2

Exclusion criteria

Exclusion criteria: Allergy to the drugs used Diabetic patients Hypertension patients Coagulation abnormality Patients with heart disease Patients with spinal deformity

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 6-12-24-36-48hours after surgery. Method of measurement: After entering the operating room, they will be fully monitored, and ECG and NIBP and pulse oximetry will be installed for them, and their venous line will be placed with an angioket number 20 from the opposite hand, which is not the side of the operation. In both groups, before starting the block, patients will be sedated with 0.02 mg/kg of midazolam and 1 microgram/kg of fentanyl. In the dexmedetomidine group, 4mg/kg of lidocaine and 1 microgram/kg of dexmedetomidine will be used in the epinephrine syringe using distilled water to a total volume of 30cc. In the sufentanil group, 4 mg/kg of lidocaine and 0.1 micro/kg of sufentanil will be used in the epinephrine syringe using distilled water to a total volume of 30 cc. Patients will be placed under supraclavicular block by ultrasound method, and hemodynamic changes will be recorded every 15 minutes during the operation. During the operation, the patient's sedation level will be recorded using the Ramsay score. The amount of postoperative pain will also be recorded at 1, 2, 6, and 12 hours after the operation with VAS SCORE.	—

Measure

Time frame

Pain. Timepoint: 6-12-24-36-48hours after surgery. Method of measurement: After entering the operating room, they will be fully monitored, and ECG and NIBP and pulse oximetry will be installed for them, and their venous line will be placed with an angioket number 20 from the opposite hand, which is not the side of the operation. In both groups, before starting the block, patients will be sedated with 0.02 mg/kg of midazolam and 1 microgram/kg of fentanyl. In the dexmedetomidine group, 4mg/kg of lidocaine and 1 microgram/kg of dexmedetomidine will be used in the epinephrine syringe using distilled water to a total volume of 30cc. In the sufentanil group, 4 mg/kg of lidocaine and 0.1 micro/kg of sufentanil will be used in the epinephrine syringe using distilled water to a total volume of 30 cc. Patients will be placed under supraclavicular block by ultrasound method, and hemodynamic changes will be recorded every 15 minutes during the operation. During the operation, the patient's sedation level will be recorded using the Ramsay score. The amount of postoperative pain will also be recorded at 1, 2, 6, and 12 hours after the operation with VAS SCORE.

—

Secondary

Measure	Time frame
Blood pressure and heart rate changes. Timepoint: Every 15 minutes during operation. Method of measurement: With pressure gauge and monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyede fatemeh hosseninejad

Ahvaz University of Medical Sciences

drhosseininejad@yahoo.com+98 61 3222 0168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026