Evaluation of the Effect of Selenium Consumption on the Immune System in Patients with non-Hodgkin Lymphoma

Evaluation of the Effect of Selenium Consumption on Th1/Th2/Th17 Lymphocyte Frequency in Patients with non-Hodgkin Lymphoma

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191023045208N1

Enrollment

Registered

2019-11-30

Start date

2018-04-21

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-Hodgkin's lymphoma patients with DLBCL subtype. Diffuse large B-cell lymphoma

Interventions

Intervention 1: Intervention group: Non-Hodgkin's lymphoma patients with DLBCL subtype who consume 200 mg of selenium tablet orally everyday for 3 months. Intervention 2: Control group: Non-Hodgkin's

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Non-Hodgkin Lymphoma with Diffuse Large B-cell Lymphoma (DLBCL) Subtype Patient being in remission phase

Exclusion criteria

Exclusion criteria: Patients with non-Hodgkin lymphoma with other disease subtype than diffuse large B-cell lymphoma (DLBCL) Patient being in active phase of the disease

Design outcomes

Primary

Measure	Time frame
Changes in the frequency of Th1 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.;Changes in the frequency of Th2 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.;Changes in the frequency of Th17 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.	—

Measure

Time frame

Changes in the frequency of Th1 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.;Changes in the frequency of Th2 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.;Changes in the frequency of Th17 lymphocytes after 3 months of selenium consumption. Timepoint: At the beginning of the study and 3 months later. Method of measurement: Flow cytometry test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nargess Arandi

Shiraz University of Medical Sciences

arandin@sums.ac.ir+98 71 3612 2263

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026