Dexmedetomidine versus remifentanil in post operative pain control after spine surgery

Comparing the effect of Dexmedetomidine and Remifentanil on post operative pain control after spine surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191023045206N1

Enrollment

Registered

2020-05-06

Start date

2019-12-01

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain. Pain, unspecified

Interventions

Intervention 1: Intervention group1:serum ringer lactate 5 ml/kg,midazolam 0.02 mg/kg,fentanyl 2mcg/kg,propofol1.5 mg/kg,atracuriom 0.5 mg/kg,morphine sulfate 0.1 mg/kg for induction and dexmedetomidi

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Elective surgery of spine age of 18-65 years ASA class 1,2

Exclusion criteria

Exclusion criteria: Previous spine surgery Opium addiction Alcohol addiction Neurological disease Neuromuscular disease Psychological disease Pulmonary disease Cardiovascular disease Analgesic consumer(cox-2 inhibitors) Operative unpredictable events (massive bleeding)

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Systolic blood pressure variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: blood pressue monitor.;Diastolic blood pressue variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: blood pressure monitoring.;Heart rate variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: heart rate monitoring.;O2 saturation variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: Pulseoxymetry.	—

Measure

Time frame

Systolic blood pressure variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: blood pressue monitor.;Diastolic blood pressue variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: blood pressure monitoring.;Heart rate variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: heart rate monitoring.;O2 saturation variance. Timepoint: 30, 60 and 120 minutes and 24 hours after surgery. Method of measurement: Pulseoxymetry.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarahzad Janatmakan

Ahvaz University of Medical Sciences

janatmakan-f@ajums.ac.ir+98 61 3374 8388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026