The effect of dexamethasone and ketamine on postoperative pain

Comparison of addition of ketamine and dexamethasone to ropivacaine in peritonsillar infiltration to reduce postoperative pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191022045200N1

Enrollment

Registered

2019-10-28

Start date

2019-04-21

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillectomy. Chronic tonsillitis and adenoiditis

Interventions

Intervention 1: First Intervention group: 2 cc of ropivacaine 0.5% plus dexamethasone 0.5 mg / kg (maximum 1 mg) with distilled water delivered to CC 10 and injected into the peritonsillar fossa by t

Eligibility

Sex/Gender

All

Age

3 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children 1 to 4 years old candidate for elective tonsillectomy Absence of underlying cardiovascular, respiratory, kidney, liver and brain diseases No history of motion sickness

Exclusion criteria

Exclusion criteria: Surgery lasts more than 4 hours Bleeding action greater than 10 cc / kg

Design outcomes

Primary

Measure	Time frame
Pain score on the Visual Analogue Scale. Timepoint: Minutes 15, 30 and 2, 4, 8, 16, 24 hours after surgery. Method of measurement: Visual Analogue Scale ruler.	—

Secondary

Measure	Time frame
Patient Agitation rate. Timepoint: Minutes 15, 30 and 2, 4, 8, 16, 24 hours after surgery. Method of measurement: Riker Sedation-Agitation scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Hoseini

Arak University of Medical Sciences

S_zeiho@yahoo.com+98 25 3774 4933

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026