Effect of Zinc in treatment of Psoriasis

Effectiveness of Zinc Supplementation on Clinical Signs of Plaque Type Psoriasis Patients with Skin Involvement Under 20%

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191022045186N1

Enrollment

Registered

2019-12-02

Start date

2019-10-22

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plaque Type Psoriasis with Skin Involvement Under 20%. Small plaque parapsoriasis

Interventions

Intervention 1: Intervention group: The intervention group will take 220mg zinc sulfate capsule once daily with topical urea eucerine emollient cream three times a day on plaques till one month. Inter

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Plaque Type Psoriasis Patients with Skin Involvement Under 20% with Serum Zinc Defficiency

Exclusion criteria

Exclusion criteria: Patients with Gastrointestinal Problems and Malabsorption Syndrome

Design outcomes

Primary

Measure	Time frame
Difference in itching of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in erythem of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in scaling of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in surface area of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in induration of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.	—

Measure

Time frame

Difference in itching of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in erythem of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in scaling of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in surface area of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.;Difference in induration of plaques. Timepoint: Before intervention, 14, 30, 60, 90, 120 days after intervention. Method of measurement: Severity mentioned by patient according to BSA and PASI indexes.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRomina Behboudi

Ardabil University of Medical Sciences

r.behboudi@arums.ac.ir+98 45 3352 0045

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026