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The effect of lycopene on serum level of cardiac biomarkers

Evaluating the effect of lycopene on cardic biomarkers, Inflammatory factors and Matrix metalloproteinase 9 in patients undering elective Percutaneous Coronary Intervention

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191018045149N1
Enrollment
50
Registered
2020-04-07
Start date
2017-12-06
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing elective coronary intervention (PCI) treatment.

Interventions

Intervention 1: Control group: PCI with standard treatment (aspirin, statin, and beta-blocker). Intervention 2: Experimental group: PCI with standard treatment (aspirin, statin, and beta-blocker) with

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient undergoing elective PCI surgery over 40 years old. Consumption of 80 to 100 mg aspirin daily for at least 5 days before PCI Completion of informed consent No Consumption of other antioxidants including vitamins C and E, coenzyme Q10, selenium, anthocyanin supplements and lycopene supplements 1 week before study No use of fish oil and omega-3 by 1 week before study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum levels of CK-MB, Troponin I and hs-CRP were measured in patients. Timepoint: Blood samples from both groups 12 hours before the intervention, 8 and 12 hours one and six months after the intervention. Method of measurement: 5 ml blood was taken from the patient to measure serum CK-MB, Troponin I and hs-CRP levels.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Rasoul Soltani

Esfahan University of Medical Sciences

soltani@pharm.mui.ac.ir+98 31 3792 7067

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026