Investigating the Effect of Sub-Tonsillar Marcaine Injection for Reducing Postoperative Nausea and Vomiting

Investigating the Effect of Sub-Tonsillar Marcaine Injection in Tonsillectomy for Reducing Postoperative Nausea and Vomiting

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191016045134N1

Enrollment

Registered

2020-02-19

Start date

2020-01-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic tonsillitis. Chronic tonsillitis

Interventions

Intervention 1: Intervention group: At the beginning of the procedure, topical injection of 1 cc bupivacaine 0.2% (20 mg/4 ml) with 0.001% epinephrine is performed by 1 cc insulin syringe. Interventio

Eligibility

Sex/Gender

All

Age

5 Years to 12 Years

Inclusion criteria

Inclusion criteria: Patients candidate for tonsillectomy surgery Age group 5 to 12 years

Exclusion criteria

Exclusion criteria: Patients with history of bronchitis and asthma Patients with history of cardiovascular, liver and hematologic diseases Allergic reaction to Bupivacaine or Lidocain Patient with history or presence of coagulation disorder (Coagulopathy) Symptoms of acute pharyngitis Acute respiratory infections The presence of fever

Design outcomes

Primary

Measure	Time frame
Postoperative pain. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: Visual Analogue Scale (VAS).;Incidence of nausea. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).;Incidence of vomiting. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).;Agitation score. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).	—

Measure

Time frame

Postoperative pain. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: Visual Analogue Scale (VAS).;Incidence of nausea. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).;Incidence of vomiting. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).;Agitation score. Timepoint: 1, 4, 8, 16 and 24 hours after drug injection. Method of measurement: By scoring in none (1), low (2), moderate (3) and Severe (4).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegar Varnaseri

Ahvaz University of Medical Sciences

Negarvarnasseri@gmail.com+98 61 3222 0168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026