Effect of ondansetron in prevention of hypotension following spinal anesthesia in cesarean section

Evaluation of Prophylactic ondansetron in prevention of maternal hypotension following spinal anesthesia in women undergoing cesarean section

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191015045121N1

Enrollment

Registered

2019-10-26

Start date

2019-12-01

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after cesarean section. Postprocedural hypotension

Interventions

Intervention 1: Intervention group: ondansetron 10 mg (Demitron, Tehran Shimi CO., Iran) will be injected intravenously 5 min before performing spinal anesthesia. Intervention 2: Control group: norma

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age between 18 to 40 years Candidate for elective cesarean section no contraindication for spinal anesthesia

Exclusion criteria

Exclusion criteria: Patients with hypertension Weight more than 100 kg Motion sickness Cardiovascular disease Liver disease Migraine Allergy to ondansetron medications group Using any medication which effect the blood pressure or heart rate

Design outcomes

Primary

Measure	Time frame
Systolic and diastolic blood pressure. Timepoint: At the beginning of the study (before the intervention) and then every 5 minutes. Method of measurement: Mercury barometer.;Side-effects after surgery. Timepoint: up to 2 hours after the patient entry to recovery. Method of measurement: presence of Itching, chills, nausea and vomiting based on direct observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Reza Mohtadi

Ahvaz University of Medical Sciences

mohtadi-ar@ajums.ac.ir+98 61 3001 3374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026