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Comparison of the therapeutic effect of intralesional injection of botulinum toxin with placebo in patients with androgenetic alopecia receiving finasteride tab

Comparison of the therapeutic effect of intralesional injection of botulinum toxin with placebo in patients with androgenetic alopecia receiving finasteride tab

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191013045092N3
Enrollment
48
Registered
2022-09-18
Start date
2022-07-25
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male androgenetic alopecia. Androgenic alopecia

Interventions

Intervention 1: In the intervention group, daily finasteride 1 mg tablets manufactured by Soha Pharmaceutical Company will be prescribed for patients, as well as 150 units of botulinum toxin type A Ma

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Being male and older than 18 years 2. Suffering from androgenic alopecia grade 3 to 5 based on the Norwood Hamilton classification and Not receiving treatment for androgenic alopecia during the last 3 months

Exclusion criteria

Exclusion criteria: 1. Severe diseases of internal organs, eyes or skin 2. Diseases of the neuromuscular system 3. Inflammation, infection or unhealed wounds on the skin around the injection site on the head 4. Receiving systematic treatment with corticosteroids or other immunosuppressants and immune modulators in the last 3 months 5. Receiving anticoagulant and antiplatelet drugs 6. Hair transplantation in the past 7. Infectious underlying disease, autoimmune, malignancy 8. Phobia about treatment with botulinum toxin 9. Reluctance to continue Study participation during treatment and follow-up

Design outcomes

Primary

MeasureTime frame
Hair density. Timepoint: Measurement of hair density at the beginning of the study and at the end of month 3 and at the end of month 6. Method of measurement: Photographing with a visioface 1000 D device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ladan Dastgheib

Shiraz University of Medical Sciences

dastgh@sums.ac.ir+98 71 3231 9049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026