acne. Acne, unspecified
Conditions
Interventions
Intervention 1: Intervention group: doxycycline (hakim company) 100 mg daily and Montelukast (abidi company) 10 mg every night + topical benzoyl peroxide 5% (pangel) on the lesions every other night f
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 35 Years
Inclusion criteria
Inclusion criteria: patients with moderate acne or acne that needs systemic antibiotic for treatment patients have not been treated with systemic medications since 1 month ago and have not been treated with topical therapy since 2 weeks ago married women accept to have contraception during treatment
Exclusion criteria
Exclusion criteria: history of hypersensitivity to the mentioned drugs inability to come regularly for follow up disagree to continue treatment under 15 and above 35 years old patients with acne conglobata and acne fulminans recieving medications that have interaction with doxycycline and montelukast pregnancy and lactation using herbal therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne severity. Timepoint: before treatment and 1,2,3 months after treatment. Method of measurement: Global acne grading system,burke and cunliffe and counting total lesion count.;Acne severity. Timepoint: before treatment and 3 months after treatment. Method of measurement: investigator global assessment score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Response to treatment. Timepoint: before treatment and 3 months after treatment. Method of measurement: asking patients.;The effect of acne on the patient's life. Timepoint: before treatment and 3 months after treatment. Method of measurement: Cardiff Acne disability index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNegin Fazelzadeh Haghighi
Shiraz University of Medical Sciences
Outcome results
None listed