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The effect of injectable albumin on renal and coagulation system activity

Comparison of the Effect of 5% Albumin Infusion with Ringer Lactate Serum on Replacement of Patients' Bleeding during Surgery on the Function of Renal and Coagulation System and Their Electrolytes after Surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191009045037N1
Enrollment
80
Registered
2019-11-30
Start date
2017-10-23
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chronic kidney disease. Condition 2: Coagulapathy. Chronic kidney disease (CKD) Coagulation defect, unspecified

Interventions

Intervention 1: Intervention group: Intraoperative fluid therapy in the this group would be albumin 5% equal to bleeding volume. To study patients' coagulation status, Prothrombin time (PT), Partial t

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Men and women 18 to 75 years The risk of anesthesia is 1 or 2 with the division of the American Anesthesia Association A blood urea of less than 38.5 mg / dl Have a blood creatinine of less than 1.3 mg / dL Blood platelets range between 150,000 and 300,000 Patient INR less than 1.2 The patient's consent form must be signed by the patient

Exclusion criteria

Exclusion criteria: Patient with a history of liver disease Patient with a history of heart failure Patient history of kidney disease Patient with a history of coagulopathy

Design outcomes

Primary

MeasureTime frame
The effect of albumin on renal system activity. Timepoint: Preoperatively and 6, 12 and 24 hours postoperatively. Method of measurement: Calometric.

Secondary

MeasureTime frame
The effect of albumin on coagulation activity. Timepoint: Preoperatively and 6,12,24 hours postoperatively. Method of measurement: Coagulometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Madineh

Shahre-kord University of Medical Sciences

hosseinmadineh@gmail.com+98 38 3226 4835

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026