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The Effectiveness of Echinacea, Listerine and Chlorhewidine mouthwashes on oral health and microbial flora.

Comparing the effectiveness of Echinacea, Listerine, and chlorhexidine mouthwashes on oral microbial flora and oral health status of patients in Intensive Care Unit.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191009045034N1
Enrollment
180
Registered
2019-12-18
Start date
2019-10-23
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microbial flora and oral hygiene of ICU patients.

Interventions

Intervention 1: Intervention group: For group A, the entire oral surface is examined with BOAS Scale and then the patient's mouth is washed with 15 cc Echinacea solution for one week and then re-exami

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: 15 to 65 years old The level of consciousness lower than 8, based on the Glasgow scale Utilizing endotracheal tube for patients’ breathing Lapsing maximum 12 hours after admitting the patient in intensive care unit

Exclusion criteria

Exclusion criteria: Having active periodontal disease Having oral Traumatic or anatomic lesions in mouth Having antibiotics two weeks before hospitalization Having systemic infections Having autoimmune or malignant diseases Radio therapy prescription Utilizing immunosuppressive drugs Allergy to mouthwashes (inflation and redness in gums and oral tissue) Patients with tracheotomy Pregnancy

Design outcomes

Primary

MeasureTime frame
The rate of oral microbial flora in unconscious patients. Timepoint: Prevalence of oral microbial flora in unconscious patients at baseline (before intervention) and one week after intervention. Method of measurement: Beck Oral Assessment Scale and Laboratory published reports of cultured and grown colonies.;Oral health status in unconscious patients. Timepoint: Oral hygiene status in unconscious patients at baseline (before intervention) and one week after intervention. Method of measurement: Beck Oral Assessment Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Kakavand Araghi

Shahroud University of Medical Sciences

simin_online.1988@yahoo.com+98 21 2795 1190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026