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Comparison of Granisetron and Ondansetrone on nausea and vomiting in adult patients

Comparison of Granisetron and Ondansetrone on nausea and vomiting in adult patients referred to the emergency department

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191007045013N1
Enrollment
200
Registered
2020-01-29
Start date
2020-01-30
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting in patients admitted to the emergency department. Nausea and vomiting

Interventions

Intervention 1: The first intervention group was injected with a conscious consent of 4 mg intravenous Ondansetron(Tehran chemistry company product) in single dose and nausea and vomiting are measu

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Nausea and vomiting in adult patients

Exclusion criteria

Exclusion criteria: Patients with symptoms such as headaches, lateralized symptoms, and unstable vital signs. Patients who have chest pain or ECG changes. Patients with symptoms of Rise ICP. Patients who have been taking sertonin (eg, fluoxetine, doxepin, isomerboxazide, amitriptyline, etc.) in the past few days. Patients who have used hepatic cytochrome P450 enzyme stimulating drugs or liver enzyme inhibitors in recent days. Patients who have consumed grapefruit in the past 24 hours Patient does not consent to attend or continue treatment.

Design outcomes

Primary

MeasureTime frame
Nausea. Timepoint: 15minute ,30minute,45minute,60minute,75 minute,90minute after to take Granisetron or Ondansetron. Method of measurement: Using a visual analogue scaling method where the patient signs a nausea rate on a line measuring 10 cm in length from zero to ten.;Vomiting. Timepoint: 15,30,45,60,75,90minute after to take Granisetron or Ondansetron. Method of measurement: Count the number of vomiting.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlivefagh Nematollahi

Ahvaz University of Medical Sciences

alivefagh@yahoo.com+98 61 3222 9166

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026