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Effect of probiotic mouthwash on chronic periodontitis

Effect of Lactobacillus salivarius NK 02 probiotic mouthwash on mild to moderate chronic periodontitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191002044957N1
Enrollment
42
Registered
2020-02-11
Start date
2019-09-23
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Control group: 10 ml of placebo mouthwash(Normal Saline) is used twice a day for 1 minute, 30 minutes after brushing for up to 1 month. Intervention 2: Intervention group: 10 ml of pro

Sponsors

Deputy of Research and Technology of Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients Referred to Periodontics Department of Zahedan Dental School, with Mild to Moderate Chronic Periodontitis The presence of envelopes between 3 and 7 mm Patient satisfaction Full public health The presence of at least 20 teeth in the mouth Lack of systemic disease (lactose intolerance, immunodeficiency disease, etc.) Lack of dry mouth Not taking any medication that affects the amount and quality of saliva No antibiotic use in the last 3 months No use of immunosuppressants in the past 6 months No smoking and other tobacco products Absence of pregnancy and lactation Non-use of other probiotic products Non-receive periodontal treatment in the last 6 months

Exclusion criteria

Exclusion criteria: Participant's unwillingness to continue treatment

Design outcomes

Primary

MeasureTime frame
Probing Depth. Timepoint: Immediately before us of mouthwash / one month later / three months later. Method of measurement: Measured by Williams probe.;Modified Gingival Index. Timepoint: Immediately before us of mouthwash / one month later / three months later. Method of measurement: Measurement by clinical examination.;Bleeding On Probing. Timepoint: Immediately before us of mouthwash / one month later / three months later. Method of measurement: Clinical observation of post-probing bleeding by Williams probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Isar

Zahedan University of Medical Sciences

Faezeakbari1375555@gmail.com+98 54 3341 5705

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026