Lycopene and wheat bran extract in melasma

Preparing skin-lightening cream containing lycopene and wheat bran extract and its clinical trail in melasma

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190930044932N1

Enrollment

Registered

2019-11-13

Start date

2019-10-07

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma. Melasma

Interventions

Intervention 1: Intervention group: cream containing tomato lycopene wheat bran extract, A cream of thirty grams every three weeks nights on stains and applying sunscreen. Intervention 2: Control grou

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Melasma diagnosis for patient Signed informed consent

Exclusion criteria

Exclusion criteria: Pregnant or lactating Use of corticosteroids and anticonvulsants and contraceptives History of allergy to wheat bran extract or lycopene Taking topical medications in the past month on face

Design outcomes

Primary

Measure	Time frame
Skin color change stain area. Timepoint: Every three weeks up to 4 months. Method of measurement: The melasma area and severity index.;Patient satisfaction. Timepoint: Every three weeks up to 4 months. Method of measurement: Descriptive in terms of patient good, moderate, poor.;Stain area. Timepoint: Every three weeks up to 4 months. Method of measurement: the melasma area and severity index.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMona Safaeizade

Ahvaz University of Medical Sciences

safaeizade.m@ajums.ac.ir+98 21 3383 3332

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026