Skip to content

Effect of Vitamin E on Dry eye

Evaluation of the Effect of Oral Vitamin E on Dry Eye; A Randomized Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190929044926N1
Enrollment
90
Registered
2019-10-09
Start date
2019-10-12
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye.

Interventions

Intervention 1: Intervention group: One capsule of Vitamin E supplement (in dosage of 400IU per day) with lunch and artificial tear drop named Tear-i (produced in Alborz Daru Company) which contains 1

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with Dry eye syndrome and questionnaire score above 10 TBUT test below 10 sec. SM Tube test below 5 mm. Age range of 18-60 years Ability and consent of the patients to take part in the study Non pregnant female participants No allergic or reaction history of taking vitamin E No history of blood coagulation disease No history of taking vitamin E supplement over the past 3 months

Exclusion criteria

Exclusion criteria: Patients with allergic or any kind of reactions with taking vitamin E Patients with blood disorders/coagulation problems Surgery history of Refractive errors

Design outcomes

Primary

MeasureTime frame
Amount of tear secretion. Timepoint: Evaluating the amount of tear secretion in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with Strip Meniscometry Test (SMTube).;Tear Break Up Time. Timepoint: Evaluating the Tear Break Up Time in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with TBUT (Tear Break Up Time) test.;Symptoms of Dry eye. Timepoint: Evaluating the symptoms of Dry eye in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with Ocular Surface Disease Index questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Moslemi Moghadam

Shahid Beheshti University of Medical Sciences

Parisamoghadam95@yahoo.com+98 21 6684 7179

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026