Burns and corrosions. Burn of unspecified body region, unspecified degree
Conditions
Interventions
Intervention 1: control group: daily application of topical formulation of silver sulfadiazine, and closed dressing. Intervention 2: Intervention group: daily application of topical treatment with si
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Second and third degree burns according to Laund & Browder criteria Minimum burn rate of patients is 10% and maximum of 50% Patients are being hospitalized in the first 24 hours of a hospital bed. informed consent to enter the study .
Exclusion criteria
Exclusion criteria: Inhalation burn Electrical and chemical burns Burns on face and hands and perineum A history of known allergies to sulfonamides History of Methemoglobinemia Pregnancy and lactation G6PD deficiency Oliguria and Anuria Functional liver disorders Lack of satisfaction with the patient to enter or continue intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90% Re-epithelialization as complete restoration. Timepoint: 7, 14, 21 and 28 days after onset of treatment with formulation. Method of measurement: The Re-epithelialization rate will also be recorded as very slow (5-6 weeks), slow (about 4 weeks), moderate (2-3 weeks), or fast (about 10 days). | — |
Secondary
| Measure | Time frame |
|---|---|
| The pain of the patient. Timepoint: once every three days. Method of measurement: The use of the visual pain criterion will be evaluated and will be graded from 0-10.;Duration of hospitalization. Timepoint: Every 5 days. Method of measurement: Based on the percentage of grafts taken on day 5.;Infection frequency. Timepoint: Every week. Method of measurement: Wound culture. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEmad Molaei
Mashhad University of Medical Sciences
Outcome results
None listed