Effect of Chitosan and Fluoride Varnish

Effect of Chitosan and Fluoride Varnish on Mutans Streptococcus levels in Saliva: a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190925044878N1

Enrollment

Registered

2020-12-22

Start date

2020-12-21

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental caries. Dental caries

Interventions

Intervention 1: Intervention group 1: 30 children for whom chitosan 5% varnish will be used. Intervention 2: Intervention group 2: 30 children for whom Chitosan 3% varnish will be used. Intervention 3

Eligibility

Sex/Gender

All

Age

4 Years to 6 Years

Inclusion criteria

Inclusion criteria: Children must be aged 4-6 years old. At the time of clinical examination, the teeth must be free of caries or have primary caries. Participants must have no history of taking antibiotics in the last month.

Exclusion criteria

Exclusion criteria: Children with a specific systemic disease Participants who have had fluoride therapy in the last 6 months.

Design outcomes

Primary

Measure	Time frame
Streptococcus mutans count in saliva. Timepoint: before intervention and 24h after intervention. Method of measurement: sterile tubes.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Basir

Ahvaz University of Medical Sciences

Basir-l@ajums.ac.ir+98 61 3373 8426

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026