"Effect of Tizanidine in reducing the pain of after septoplasty"

Comparison of the effectiveness of oral Tizanidine in severity of pain after Septoplasty, in two groups of drug and placebo

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190921044831N1

Enrollment

Registered

2019-12-27

Start date

2014-04-09

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deviation of nasal septum. Deflection or deviation of septum (nasal)(acquired)

Interventions

Intervention 1: Intervention group: Oral Tizanidine tablet 4 mg (Hakim Pharmacy Company) 2 hours before surgery. Intervention 2: Control group: Placebo, Oral Vitamin B1 100 mg tablet (Poursina Pharm

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with septoplasty class 1 or/and 2 ASA Not history of gastric ulcer Not history of using corticosteroids or other immune system suppressors

Exclusion criteria

Exclusion criteria: Allergy to Tizanidine Age 50 y Re-Septoplasty Sinorhinoplasty Contraindication of Tizanidine therapy Cases that need to be treated differently by anesthesia or surgery Addiction Hepatic or renal disorder Cases of ASA 3

Design outcomes

Primary

Measure	Time frame
Pain of after septoplasty surgery. Timepoint: After 4, 8 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact??? ???? ????

Kerman University of Medical Sciences

a_arabi@kmu.ac.ir+98 34 3132 5856

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026