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The effect of propranolol on post-traumatic stress and clinical outcomes in burn patients

The effect of propranolol on post-traumatic stress and clinical outcomes in burn patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190919044819N2
Enrollment
52
Registered
2020-09-13
Start date
2020-08-15
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burn. Burn of second degree of chest wall, subsequent encounter

Interventions

Intervention 1: Intervention group: The intervention in this study includes the administration of propranolol by a physician specializing in burns and after consultation with the advice of a cardiolog

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Able to talking Wounds that are 20 to 50 percent of the total body surface area of TBSA And have wounds that are second and third degree Requires treatment with at least one skin graft surgery Receive propranolol for at least 4 consecutive days 48 hours after hospitalization in the intervention group Satisfaction with participating in data collection

Exclusion criteria

Exclusion criteria: Medical conditions Contraindications to propranolol (beta-blocker contraindication) pregnancy bipolar disorder, head injury cardiopulmonary disease, endocrine and peripheral, asthma, systolic blood pressure less than 90, heart rate 60, inhalation damage 5 years of malignancy, history of AIDS, diabetes

Design outcomes

Primary

MeasureTime frame
Post-traumatic stress. Timepoint: At the beginning of the study (before the intervention) and And one month after the intervention. Method of measurement: Impact of Event Scale-Revised.

Secondary

MeasureTime frame
Successful skin grafting. Timepoint: Both groups will be evaluated within two weeks and four weeks after discharge. Method of measurement: Clinical examination in which the evaluation of the success of the transplant means a transplant that is pink in color and firmly attached to the base of the transplant area.;Duration of hospitalization. Timepoint: The first and last day of hospitalization in the ward. Method of measurement: Counting by number of days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeili Yekefallah

Qazvin University of Medical Sciences

Leili_fallah@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026