Direct electrical stimulation of the brain in obsessive-compulsive disorder

Efficacy of transcranial direct stimulation on amplifation of neuropsychological function in patient with obsessive-compulsive disorder: A double-blind randomize clinical trial with the control group

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190917044793N2

Enrollment

Registered

2022-01-15

Start date

2022-02-09

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention group: in this group, participants will receive supraorbital left cathodal-cortex and frontal inferior right anodal tDCS stimulation for 20 sessions of 20 minutes in 10 da

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Diagnosis ofobsessive-compulsive disorder based on DSM V Age: 18-50 years old Required written informed consent signed by patients' guardian

Exclusion criteria

Exclusion criteria: History of neurological diseases such as seizures, strokes, or cerebrovascular diseases The existence of metal implants in the body Pregnancy

Design outcomes

Primary

Measure	Time frame
Neuropsychological function. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Working memory. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Inhibition response. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Cognitive flexibility. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Executive functions. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Test Wisconsin Cards.;Severity of obsessive-compulsive symptoms. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Maudsley Obsessional-Compulsive Inventory.;Evaluation of anxiety symptoms. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Beck Anxiety Inventory (BDI).	—

Measure

Time frame

Neuropsychological function. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Working memory. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Inhibition response. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Cognitive flexibility. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Cambridge Neuropsychological Test Automated Battery (CANTAB).;Executive functions. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Test Wisconsin Cards.;Severity of obsessive-compulsive symptoms. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Maudsley Obsessional-Compulsive Inventory.;Evaluation of anxiety symptoms. Timepoint: Before intervention (baseline 1, 2). after the intervention.14, 30 and 90 days after the intervention. Method of measurement: Beck Anxiety Inventory (BDI).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Anita Azarkolah

Ardabil University of Medical Sciences

dra.azarkolah@gmail.com+98 45 3323 2520

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026