Comparison of Ondansetron and Dexamethasone Versus Dexamethasone efficacy On Postoperative nausea and vomiting in patients with maxillofacial trauma refered to "Shohadaye Ashayer" hospital of Khorramabad

Comparison of Ondansetron and Dexamethasone Versus Dexamethasone efficacy On Postoperative nausea and vomiting in patients with maxillofacial trauma

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190916044784N2

Enrollment

Registered

2023-05-25

Start date

2023-06-22

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maxillofacial trauma. Fracture of skull and facial bones

Interventions

Intervention 1: Intervention group: Intervention group: For all the studied patients, after entering the operating room (both the intervention group and the control group), an IV line will be installe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients referred to the "Shohadaye Ashayer" Hospital who have maxillofacial trauma and require surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: Patients who underwent another operation under general anesthesia 24 hours before maxillofacial surgery. Patients who have lost consciousness for any reason after trauma. Patients with ASA=III. Patients with a history of Motion sickness or recent vomiting. Patients who have severe hypotension and bradycardia while surgery, and need intraoperative blood transfusion or postoperative ICU. Patients with hypersensitivity or allergy to any of the studied drugs.

Design outcomes

Primary

Measure	Time frame
Nausea and vomiting. Timepoint: 1, 2, 6, 12 and 24 hours after surgery. Method of measurement: Direct questions from patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKosar Rostampur

Khoram-Abad University of Medical Sciences

kosar_rostampur@yahoo.com+98 66 3321 8502

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026