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Evaluation the Effects of Melatonin on Amount of Opioids Intake

Evaluation the Effects of Melatonin versus Placebo on Amount of Opioids Intake in Patients Admitted to Intensive Care Unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190912044752N1
Enrollment
52
Registered
2019-10-28
Start date
2019-09-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic patients.

Interventions

Intervention 1: Intervention group: On arrival at the intensive care unit, the patients will be received melatonin with dose of 3 mg every night until discharge. Intervention 2: Control group: On arri

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age range 18 – 80 year Traumatic patients who are admitted to intensive care unit

Exclusion criteria

Exclusion criteria: Patients with GCS less than 4 Pregnant patients Patients with renal and liver failure Patients with brain tumor Allergic reaction to melatonin

Design outcomes

Primary

MeasureTime frame
The amount of prescribed opioid analgesic medication. Timepoint: Daily from admission and starting intervention to discharge. Method of measurement: Total receiving dose of opioid analgesic medication.;Duration of hospitalization. Timepoint: Duration of admission to discharge. Method of measurement: Checklist.;The time required for mechanical ventilation. Timepoint: Duration of hospitalization. Method of measurement: Checklist.;Rate of mortality. Timepoint: Duration of hospitalization. Method of measurement: The number of patients who died.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarahmand Kalantari

Ahvaz University of Medical Sciences

farahmandbm@gmail.com+98 61 3374 3037

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026