Investigating the effectiveness of garlic in the prevantion of nephropathy

Evaluation of the effectiveness of garlic in the prevention of contrast induced nephropathy in following coronary angiography

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190911044744N5

Enrollment

Registered

2024-03-07

Start date

2024-02-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of nephropathy. Nephrotic syndrome

Interventions

Intervention 1: Intervention group: recipients of 500 mg garlic tablets from Gol Daru company, took one tablet orally 12 hours before angiography to reduce nephrotoxicity of the contrast material and

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and above Patient hospitalized in Afshar Hospital undergoing coronary artery angioplasty Not receiving nephrotoxic drugs Not taking garlic-containing drugs in the past one month No history of allergy to garlic Tolerating the use of oral drugs Hospitalization in the special heart care unit for 2 days Informed consent of the patient or his legal guardian

Exclusion criteria

Exclusion criteria: Pregnant or lactating mother Allergy to garlic Anticoagulant medication in the last 2 week

Design outcomes

Primary

Measure	Time frame
Nephropathy rate. Timepoint: 48 hours after the operation. Method of measurement: Examining serum creatinine levels in patient tests.	—

Secondary

Measure	Time frame
Serum creatinine levels. Timepoint: 48 hours after operation. Method of measurement: Examining serum creatinine levels in patient tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Mirzaei

Yazd University of Medical Sciences

Ehsan.mirzaei.1369@gmail.com+98 35 2038 1934

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026