Liver Trauma. Contusion of liver
Conditions
Interventions
Intervention 1: Intervention group: Receiving Livergol tablet 140 mg Goldaru factory orally every eight hours for 14 days yo reduce liver enzyme levels. Intervention 2: Control group: Receiving placeb
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: People aged 16 or over Not taking a known hepatotoxic drug Not taking oral silymarin during the past day No confirmed history of allergic reactions following oral administration of silymarin Alanine aminotransferase (ALT) levels more than 2-fold above normal (> 70 IU / L) up to 4-fold above normal Or aspartate aminotransferase (AST) levels more than 2-fold above normal (> 70 IU / L) up to 4-fold above normal Not taking concomitant antioxidants or compounds such as vitamin A, C, E and N-acetyl cysteine Oral tolerance to medications
Exclusion criteria
Exclusion criteria: Pregnancy or lactation History of advanced liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreased liver enzyme levels. Timepoint: Start of study, end of first week, end of second week. Method of measurement: Blood test.;Measurement of free radicals. Timepoint: The beginning and the end of the study. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Mirzaei
Shiraz University of Medical Sciences
Outcome results
None listed