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Comparison of the effect of epinephrine injection in rhinoplasty

Comparison of the effect of epinephrine injection with two different concentrations on hemodynamic changes and bleeding rate of rhinoplasty in patients under general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190911044743N1
Enrollment
60
Registered
2020-06-14
Start date
2020-06-21
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

effect of subcutaneus epinephrine on hemodynamic changes and bleeding in rhinoplasty.

Interventions

Intervention 1: Intervention group: solution of subcutaneus epinephrine 1/200000 with lidocaine 2%. Intervention 2: Control group: subcutaneus epinephrine 1/100000 with lidocaine 2%.

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 45 Years

Inclusion criteria

Inclusion criteria: People aged 16-45 years ASA I,II

Exclusion criteria

Exclusion criteria: Coagulation disorder Heart disease hypertension Cerebrovascular disease Renal disease drug Allergies

Design outcomes

Primary

MeasureTime frame
Systolic and diastolic and mean arterial pressure. Timepoint: Before inductin by anesthesia, after intubation and then at intervals before anesthesia, after intubation, immediately before epinephrine injection, and then every minute to the third minutes after injection, and then every 5 minutes until the end of the procedure. Method of measurement: Non-invasive automatic measurement by a monitoring device.;Heart rate. Timepoint: Before inductin by anesthesia, after intubation and then at intervals before anesthesia, after intubation, immediately before epinephrine injection, and then every minute to the third minutes, and then every 5 minutes until the end of the procedure. Method of measurement: EKG monitoring.;Rate of bleeding. Timepoint: End of surgury. Method of measurement: Measurment of blood in bottle of suction and number of bloody gases.

Secondary

MeasureTime frame
Volume of infused propofol. Timepoint: End of surgery. Method of measurement: Volume of infusion in milliliter.;Volume of infused remifentanil. Timepoint: End of surgery. Method of measurement: Volume of infusion in milliliter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadeseh Ahmadi

Kerman University of Medical Sciences

mohadeseh7265@gmail.com+98 34 3325 7660

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026