Thyroid Electrical Impedance Spectroscopy

Clinical trial of Electrical Impedance Spectroscopy of Thyroid nodules for real-time discrimination of benign, atypical, and malignant lesions in patients candidate for surgery or biopsy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190904044697N7

Enrollment

384

Registered

2021-02-16

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Malignant neoplasm of Thyroid. Condition 2: Benign tumor with solid mass. Condition 3: Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck. Malignant neoplasm of Thyroid Benign neoplasm of thyroid gland Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck

Interventions

Intervention 1: Intervention group 1: Our surgical colleagues select some patients with solid tumors that are candidates for surgery and applying ETS based on inclusion criteria. After anesthetizing t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients candidate for Thyroid surgery Patients candidate for Parathyroid surgery Patients candidate for dissection of neck lymph nodes Patients candidate for Thyroid biopsy Patients candidate for neck lymph nodes biopsy

Exclusion criteria

Exclusion criteria: No exclusion criteria for patients candidate for Thyroid surgery High blood pressure patients (for ETS tests before biopsy) Patients taking anticoagulants (for ETS tests before biopsy)

Design outcomes

Primary

Measure	Time frame
The pathologic classification of thyroid nodules or metastatic neck lymph nodes. Timepoint: before dissection of the thyroid nodule, suspicious lymph node or parathyroid nodule for patients candidate for surgery / before FNA or CNB from thyroid nodule or suspicious lymph nodes for patients candidate for biopsy. Method of measurement: Electrical Impedance Spectroscopy (impedance phase slope in frequency ranges of 100kHz to 500 kHz).	—

Measure

Time frame

The pathologic classification of thyroid nodules or metastatic neck lymph nodes. Timepoint: before dissection of the thyroid nodule, suspicious lymph node or parathyroid nodule for patients candidate for surgery / before FNA or CNB from thyroid nodule or suspicious lymph nodes for patients candidate for biopsy. Method of measurement: Electrical Impedance Spectroscopy (impedance phase slope in frequency ranges of 100kHz to 500 kHz).

—

Secondary

Measure	Time frame
Investigation of ETS in decreasing unrequired biopsy or surgery of benign thyroid lesions. Timepoint: after finishing the trial. Method of measurement: By comparing FNA pathology results and impedance spectroscopy results of patients candidate for thyroid surgery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Abdolahad

Tehran University of Medical Sciences

m.abdolahad@ut.ac.ir+98 21 8802 8367

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026