Intra-operative real-time diagnostic system for suspicious breast tissue using electrochemical signaling as a complementary method for frozen section pathology

In-vivo intra-operative detection of breast margins involved in cancer using hypoxia glycolysis metabolism as neoplastic signaling. A frozen guided clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190904044697N3

Enrollment

Registered

2020-02-23

Start date

2020-02-04

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer surgery. Malignant neoplasm of breast

Interventions

Intervention group: The surgeon follows the standard guidelines based on frozen pathology, and will apply CDP as a complementary diagnostic tool to check the inner margins after completing the surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with noticeable breast tumor mass or previously diagnosed with solid mass (DCIS, ILC, IDC...).

Exclusion criteria

Exclusion criteria: No exclusion regarding patients recruitment

Design outcomes

Primary

Measure	Time frame
The pathological classification of different breast lesions correlates with current peaks of CDP. Results show meaningful consistency between DIN (Ductal Intraepithelial Neoplasia) based pathological diagnosis and CDP scoring. Timepoint: Results will be compared with permanent pathology 3 days after the intervention. Method of measurement: Electrochemical Cyclic voltammetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Abdolahad

Tehran University of Medical Sciences

m.abdolahad@ut.ac.ir+98 21 8802 8367

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026