Intra-operative real-time diagnostic probe for suspicious legions using electrochemical tracing of hypoxia glycolysis

Real-time intra-operative in-vivo diagnosis of internal margins involved to breast pre-invasive/invasive cancer cells through pathological classification using a handheld electrochemical system

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190904044697N1

Enrollment

200

Registered

2019-10-01

Start date

2018-08-25

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer surgery. Malignant neoplasm of breast, Breast cancer surgery, Hyperplasia

Interventions

Intervention group: After tumor dissection, all the regions in body side margins named internal margins are tested by CDP. Depend on the size of the tumor and its proximity to one of the margins (not

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with obvious breast tumor mass, previously diagnosed with solid mass (DCIS, ILC, IDC...). Neo-adjuvant cases with or without a wire guide.

Exclusion criteria

Exclusion criteria: No exclusion regarding patients recruitment

Design outcomes

Primary

Measure	Time frame
Pathological classification of different breast lesions correlated with current peaks of CDP. Results show meaningful consistency between DIN (Ductal Intraepithelial Neoplasia) based pathological diagnosis and CDP scoring. Timepoint: Results will be compared with permanent pathology about 2 weeks after intervention. Method of measurement: Electrochemical Cyclic voltammetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Abdolahad

Tehran University of Medical Sciences

m.abdolahad@ut.ac.ir+98 21 8802 8367

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026