Postoperative nausea and vomiting in patients undergoing elective laparoscopy; comparison of total intravenous anesthesia versus inhalational anesthesia; a randomized clinical trial

Comparison of Postoperative Nausea and Vomiting (PONV) with Total Intravenous Anesthesia (TIVA) versus Inhalational Anesthesia in patients undergoing Elective Laparoscopy in Imam Khomeini Hospital Complex-Tehran (IKHC)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190904044685N2

Enrollment

100

Registered

2019-10-12

Start date

2018-08-23

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting. Vomiting following gastrointestinal surgery

Interventions

Intervention 1: Intervention group: Total intravenous anesthesia. In the intravenous group, 50cc of Propofol 1% was combined with 1-2cc of Remifentanil and was intravenously infused at the speed of 15

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA class I ASA class II Elective laparoscopy

Exclusion criteria

Exclusion criteria: History of motion sickness History of PONV Positive drug Allergy history Unwillingness of the patient

Design outcomes

Primary

Measure	Time frame
Incidence and severity of postoperative nausea and vomiting. Timepoint: 0, 2, 6, 12, 24 hours after surgery. Method of measurement: Standardized questionnaire, Verbal/Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKasra Karvandian

Tehran University of Medical Sciences

karvandian@tums.ac.ir+98 21 6119 2619

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026